PromoFectin provides highly effective and reliable delivery of nucleic acids into a variety of cell types, including many hard-to-transfect cell lines and primary cells such as human endothelial cells, fibroblasts and hepatocytes. It consists of a proprietary non-liposomal, cationic polymer that is stable, water-soluble and free of any components of animal origin. In contrast to many liposome-based transfection reagents, it shows very low toxicity and is therefore ideally suited even for transfection of very sensitive cells yielding optimal transfection efficiencies and gene expression. Transfection with PromoFectin typically requires no medium change and it can be used for highly effective delivery of plasmid DNA as well as oligonucleotides and siRNA into adherent and non-adherent cells. It compacts DNA into positively-charged, stable and protective complexes which bind to negatively-loaded cell-surface residues and enter the cell by endocytosis. In the endosome, PromoFectin acts as a “proton sponge”, buffering the endosomal pH that leads to pH inhibition of endosomal nucleases and ensures stability of the complexes. Continuous proton influx leads to osmotic swelling and rupture of the endosome, allowing a very rapid and almost complete release of the nucleic acids into the cytosol. Moreover, PromoFectin also favors DNA trafficking to the cell nucleus – a property that is particularly useful for transfection of slow-dividing or resting cells.
Promokine代理
,简介:蚂蚁淘生物公司做为Promokine代理,专业经营原装进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗等。
Promokine代理的产品涉及分子生物学、细胞生物学、细菌学、遗传学、免疫学、生物化学、蛋白质学、细胞治疗、临床应用等领域。做为代理,我们郑重承诺:保证原装进口,如出现运输质量问题,我们可以包退换货。
代理,所能提供产品如下:
Recombinant Human ULBP-2 Fc Chimera, CF (50 UG),R&D 货号:1298-UL-050,规格:50 UG
Recombinant Human NKG2D Fc Chimera, CF (50 UG),R&D 货号:1299-NK-050,规格:50 UG
Recombinant Mouse MD-1 (50 UG),R&D 货号:130-MD-050,规格:50 UG
Recombinant Mouse MD-1, CF (50 UG),R&D 货号:130-MD-050/CF,规格:50 UG
Recombinant Human MICA Fc Chimera, CF (50 UG),R&D 货号:1300-MA-050,规格:50 UG
Recombinant Mouse Galectin-7 (50 UG),R&D 货号:1304-GA-050,规格:50 UG
Recombinant Mouse Galectin-7, CF (50 UG),R&D 货号:1304-GA-050/CF,规格:50 UG
Recombinant Human Galectin-8 (50 UG),R&D 货号:1305-GA-050,规格:50 UG
Recombinant Human Galectin-8, CF (50 UG),R&D 货号:1305-GA-050/CF,规格:50 UG
Recombinant Rat Erythropoietin (10 UG),R&D 货号:1306-RE-010,规格:10 UG
Recombinant Rat Erythropoietin, CF (10 UG),R&D 货号:1306-RE-010/CF,规格:10 UG
Recombinant Mouse Frizzled-2 Fc Chimera, CF (50 UG),R&D 货号:1307-FZ-050,规格:50 UG
Recombinant Mouse Notch-3 Fc Chimera, CF (50 UG),R&D 货号:1308-NT-050,规格:50 UG
Recombinant Mouse Prolactin R Fc Chimera, CF (50 UG),R&D 货号:1309-PR-050,规格:50 UG
Recombinant Human CCL23/MPIF-1 (aa 46-120) (25 UG),R&D 货号:131-M1-025,规格:25 UG
Recombinant Human CCL23/MPIF-1 (aa 46-120), CF (25 UG),R&D 货号:131-M1-025/CF,规格:25 UG
Recombinant Human u-Plasminogen Activator/Urokinase, CF (10 UG),R&D 货号:1310-SE-010,规格:10 UG
Recombinant Rat IFN-alpha (100000 UN),R&D 货号:13100-1,规格:100000 UN
Recombinant Human Sonic Hedgehog/Shh, N-Terminus (25 UG),R&D 货号:1314-SH-025,规格:25 UG
Recombinant Human Sonic Hedgehog/Shh, N-Terminus, CF (25 UG),R&D 货号:1314-SH-025/CF,规格:25 UG
Recombinant Mouse Nodal (25 UG),R&D 货号:1315-ND-025,规格:25 UG
Recombinant Mouse Nodal, CF (25 UG),R&D 货号:1315-ND-025/CF,规格:25 UG
Recombinant Rat IL-22 (10 UG),R&D 货号:1316-RL-010,规格:10 UG
Recombinant Rat IL-22, CF (10 UG),R&D 货号:1316-RL-010/CF,规格:10 UG
Recombinant Mouse Thrombopoietin R Fc Chimera, CF (50 UG),R&D 货号:1317-TR-050,规格:50 UG
Recombinant Rhesus Macaque IL-1 beta/IL-1F2 (10 UG),R&D 货号:1318-RL-010,规格:10 UG
Recombinant Rhesus Macaque IL-1 beta/IL-1F2, CF (10 UG),R&D 货号:1318-RL-010/CF,规格:10 UG
Recombinant Human TL1A/TNFSF15 (10 UG),R&D 货号:1319-TL-010,规格:10 UG
Recombinant Human TL1A/TNFSF15, CF (10 UG),R&D 货号:1319-TL-010/CF,规格:10 UG
Bovine FGF acidic (25 UG),R&D 货号:132-FA-025,规格:25 UG